Statistics question residual risk

Mark H Ebell ebell at UGA.EDU
Mon Sep 7 20:31:16 UTC 2015


Yes, as you define it, residual risk is the converse of negative predictive value. It is also post test probability of disease given a negative test.

Mark Ebell

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On Mon, Sep 7, 2015 at 1:00 PM -0700, "Twest54973" <000000040134e744-dmarc-request at LIST.IMPROVEDIAGNOSIS.ORG<mailto:000000040134e744-dmarc-request at LIST.IMPROVEDIAGNOSIS.ORG>> wrote:

Can this question be posted on the list serve?

Residual risk (used in the context of a screening test which gives dichotomous results ie, positive or negative)  is usually defined as the risk of disease after a negative result on the screening test

I am looking for a formula to calculate residual risk using sensitivity, specificity, and pretest probability (akin to the formulas that exist for PPV and NPV)

I have seen some authors state that residual risk = 1- NPV

Is there another way to calculate RR?

How would you modify the RR calculation if the screening test could potentially give three results positive or negative or uninformative?

Thank you
Tom Westover MD



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